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Variable Pressure Support Trial | Clinical Trials | Clareo Health

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TERMINATEDNANCT01769053

Variable Pressure Support Trial

In 2008 a new ventilation strategy termed variable Pressure Support ventilation (PSV) was introduced, which is able to increase the variability of the respiratory pattern independent from the inspirat...

Lead sponsor: Technische Universität Dresden•1 locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

Technische Universität Dresden

Collaborators

Medical University of Vienna
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
University Hospital, Montpellier
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
IRCCS Azienda Ospedaliera Universitaria San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy
St Thomas' Hospital, London
Hospital Sirio-Libanes
Hospital Copa D'Or, Rio de Janeiro, Brazil
Hospital Universitari Sant Joan de Reus
University of Kiel
Fachkrankenhaus Coswig GmbH

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•Age ≥ 18 years
•Duration of controlled mechanical ventilation ≥ 24h
•Availability of a Infinity V500 ventilator (ready to use)
•Informed consent according to local regulations
•Temperature ≤ 39 °C
•Hemoglobin ≥ 6 g/dl
•PaO2/FIO2 ≥ 150 mmHg with positive end-expiratory pressure (PEEP) ≤16 cmH2O
•Ability to breath spontaneously

Exclusion Criteria

•Participation in another interventional trial within the last four weeks before enrollment in this trial
•Peripheral neurological disease associated with impairment of the respiratory pump
•Muscular disease associated with impairment of the respiratory pump
•Instable thorax with paradoxical chest wall movement
•Planned surgery under general anesthesia within 72 hours
•Difficult airway/intubation
•Existing tracheotomy at ICU admission
•Expected survival \< 72 hours
•Home mechanical ventilation or on chronic oxygen therapy
•Suspected pregnancy

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: July 26, 2018Terms

Trial snapshot

StatusTERMINATED

PhaseNA

Enrollment130

Start dateJan 2013

Last updatedJul 26, 2018

Condition

Acute Lung Injury Adult Respiratory Distress Syndrome at Least 24 h of Controlled Mechanical Ventilation

Locations shown

Department of Anesthesiology and Intensive Care, Dresden University of Technology

Dresden

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: July 26, 2018Data synced to Clareo: May 10, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions