Ex Vivo Stimulation of Whole Blood as a Means to Determine Glucocorticoid Sensitivity to Mild-to-Moderate and Refractory Asthmatics

Inclusion Criteria

• •To be eligible for the study, subjects must meet all of the following criteria:
• •Age ≥ 18 years old
• •Physician diagnosis of asthma confirmed through medical record documentation.
• •Documented history of 12% FEV1 reversibility post-bronchodilator and/or Methacholine PC 20 score of 16mg/ml or less.
• •Non-smoker for \> 6 months before enrollment into the trial
• •Less than 5 pack year smoking history defined as the average packs smoked per day multiplied by the years of active smoking.
• •Willing and able to adhere to the study visit schedule and other protocol-specified procedures.