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Vitamin D Supplementation in Obesity and Weight Loss (3DD Study) | Clinical Trials | Clareo Health

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Vitamin D Supplementation in Obesity and Weight Loss (3DD Study)

A Pilot Dose Response Study to Vitamin D in Obesity and Weight Loss: Effect on Bone

NCT01631292•Rutgers University

Summary

In this study, we will provide supplemental vitamin D in postmenopausal overweight/obese women, and hypothesize that it will not affect areal BMD, but will alter bone compartments (trabecular and cortical bone). In addition, higher vitamin D intake will increase serum 25OHD and suppress serum PTH and bone turnover during weight reduction. Secondary outcomes include the influence of vitamin D and weight loss on markers of insulin resistance and on cognitive tests of attention, learning, and memory.

Eligibility

Age

50 - 72 years

Sex

FEMALE

Healthy Volunteers

Yes

Inclusion Criteria

•Body mass index of 25-40 kg/m2
•Postmenopausal
•Age 50-72 years

Exclusion Criteria

•Women who are taking any medication known to influence Calcium or bone metabolism,
•Evidence of diseases known to influence Calcium metabolism (i.e. metabolic bone disease)
•hyperparathyroidism
•untreated thyroid disease
•significant immune disease
•hepatic disease
•renal disease or a kidney stone in the last 5 years
•significant cardiac disease
•active malignancy or cancer therapy within the past year

Locations (1)

Rutgers University- Thompson Hall

New Brunswick, New Jersey, United States

Key Dates

Start Date

January 1, 2010

Primary Completion Date

May 1, 2015

Completion Date

December 30, 2019

Last Updated

November 22, 2023

Enrollment

ACTUAL participants

Conditions

Osteoporosis

Interventions

600 IU Vitamin D3

DIETARY_SUPPLEMENT

2000 IU Vitamin D3

DIETARY_SUPPLEMENT

4000 IU Vitamin D3

DIETARY_SUPPLEMENT

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: November 22, 2023Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

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Vitamin D Supplementation in Obesity and Weight Loss (3DD Study)

Inclusion Criteria

Exclusion Criteria

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