History of Cushing's disease or syndrome, or Addison's disease

Glycosylated hemoglobin (HbA1c) ≥10%

Cerebrovascular insult, unstable angina, or myocardial infarction (MI) within 6 months

History of impaired renal or hepatic function

BMI ≥50 kg/m2

Any injectable antihyperglycemic agent (such as insulin) within 16 weeks

Currently receiving more than one class of antihypertensive agents within 4 weeks

Daily use of nonsteroidal anti-inflammatory agents within 1 week

Use of androgen medications, including topical preparations, within 6 weeks

Diagnosis or history of breast cancer

Safety and Efficacy Study of BMS-823778 to Treat Uncontrolled High Blood Pressure in Overweight and Obese Patients