Combined Rg3-enriched Korean Red Ginseng and American Ginseng in the Management of Hypertension in Type 2 Diabetes

Exclusion Criteria

• •insulin therapy
• •history of angina, myocardial infarction or stroke
• •systolic blood pressure \>160 mmHg and/or diastolic blood pressure \>100 mmHg
• •use of ginseng within 1 month start of study
• •BMI \>35 kg/m2
• •smoking cigarettes
• •alcohol intake of \> 2 drinks/day
• •recently given blood
• •have an upcoming planned surgery
• •GFR \<60 mL/min/1.73m2
• •prolonged QT (\>20 ms) interval as assessed by ECG
• •changes to use of natural health products that may effect blood pressure and/or diabetes
• •weight change more than +/- 3 kg/month
• •HIV infection, inflammatory bowel disease, celiac disease, heart disease, bleeding disorder, sleep disorder, arrhythmia
• •pregnant or breastfeeding
• •use of anticoagulant (excluding aspirin), antiplatelet, sedative, sympathomimetic, photosensitizing or anti-depressant drugs
• •hormone replacement therapy, furosemide, morphine, glucocorticoids
• •presence of any conditions which, in the opinion of the Qualified Investigator, might jeopardize the health and safety of the subject or study personnel, or adversely affect the study results
• •known sensitivity or allergy to any test product or placebo ingredients