The Effect of Vitamin C on Growth Hormone Secretion

Exclusion Criteria

• •1. History of hypopituitarism, pituitary surgery, pituitary/brain radiation, recent traumatic brain injury or any other condition known to affect the GH axis.
• •2. History of severe chronic illness including anemia, chronic kidney disease, liver disease, oxygen dependent COPD or HIV
• •3. Subjects on testosterone, glucocorticoids, anabolic steroids, GHRH, GH or IGF-1 within 3 months of enrollment
• •4. Use of dietary supplements including vitamin C or once daily multi-vitamins
• •5. Subjects with Hgb \< 912 g/dL, SGOT \> 2.5x upper limit of normal or Creatinine \> 1.5 mg/dL
• •6. Subjects with poorly controlled diabetes, defined as HbA1c \> 8%.
• •7. Changes in lipid lowering or anti-hypertensive regimen within 3months of screening
• •8. Subject is currently enrolled in another investigational device or drug trial(s), or subject has received other investigational agent(s) within 28 days of baseline visit
• •9. Any condition judged by the patient's physician to cause this clinical trial to be detrimental to the patient.