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COMPLETEDNCT01472471

Urinary 8-isoprostane is Elevated in Acute Childhood Asthma

Oxidative stress is seen in children with asthma, but is hard to measure. The investigators exploring the utility of using a commercially available assay to measure oxidative stress in the urine in as...

Lead sponsor: Stony Brook University•1 U.S. locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

Stony Brook University

Age

4 - 18 years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•Group 1
•1. Patients aged 4-18 years
•2. Known stable asthmatics on no medications or with no medication changes in 3 weeks prior to enrollment
•3. No asthma hospitalizations in past 3 months
•4. Parent available to consent
•Group 2
•1. Patients aged 4-18
•2. Known asthmatic, admitted to Stony Brook University Hospital for status asthmaticus
•3. Parent available to consent

Exclusion Criteria

•1. Any child with documented fever within 24 hours of study entry
•2. Any child with a known current history of tracheo- or bronchomalacia
•3. Any child with known clinical or laboratory evidence of shock (see below)
•4. Any child with history of documented immunodeficiency, rheumatologic disease, cystic fibrosis, or renal dysfunction (see below)
•5. Any child with a current or recent (less than 1 year) history of tracheostomy
•6. Any child with a known genetic abnormality
•7. Any pregnant child
•8. Any child with a history of autism
•9. Any child whose parent/caregiver is unable to give informed consent

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: June 6, 2013Terms

Trial snapshot

StatusCOMPLETED

Phase—

Enrollment52

Start dateNov 2010

Last updatedJun 6, 2013

Condition

Childhood Asthma Oxidative Stress

Locations shown

Long Island Children's Hospital at Stony Brook

Stony Brook, New York

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: June 6, 2013Data synced to Clareo: May 17, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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