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Recent studies on molar surgery have shown that a combination of a glucocorticoid and NSAID or COX-2 selective inhibitor gives better pain relief than either of the drugs used separately. The investigators group has also shown that adding dexamethasone on top of a regimen of paracetamol, NSAID and local anesthesia resulted in 45% painfree patients at rest after ambulatory breast cancer surgery. The goal of this study is to test the NSAID + glucocorticoid concept in ACl repair. The investigators want to evaluate whether a selective COX-2 selective inhibitor or a glucocorticoid or a combination of both drugs, as part of a multimodal analgesic regime, can provide improved pain relief and shorter hospital stay in patients undergoing outpatient ACL surgery.
Age
18 - 90 years
Sex
ALL
Healthy Volunteers
No
Baerum Hospital
Rud, Norway
Start Date
January 1, 2004
Primary Completion Date
December 1, 2009
Completion Date
December 1, 2009
Last Updated
May 27, 2011
93
ACTUAL participants
parecoxib, valdecoxib, etoricoxib
DRUG
Dexamethasone
DRUG
parecoxib, valdecoxib, parecoxib and dexamethasone
DRUG
Lead Sponsor
Asker & Baerum Hospital
NCT02511158
NCT00463099
Data Source & Attribution
This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.
Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.
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