Lead Sponsor

University of Michigan

Collaborators

Age

18 - 35 years

Sex

MALE

Healthy Volunteers

No

•Males between the ages of 18 and 35
•Have acute unilateral complete ACL tears with or without bucket handle medial meniscus tears that occurred within the past 6 months
•Consent to undergo an ACL reconstruction by an orthopaedic surgeon using a patellar tendon or hamstring autograft
•Will be performing supervised post-operative rehabilitation at UMHS MedSport at Dominos Farms

•Patients who are undergoing a revision ACL reconstruction
•Had a previous injury to the involved knee
•Have an allergy to recombinant GH
•Have a BMI\<20 or \>35
•Have a growth disorder of bones or connective tissue, type 1 diabetes mellitus, type 2 diabetes mellitus, or who have a history of carpal tunnel syndrome, trigger finger, myopathy, cancer, endocrine disorder, hypertension or rheumatologic disorder.
•Systolic blood pressure \>140mm Hg or diastolic blood pressure \>90mm Hg, or with resting heart rate \>110 BPM or \<40 BPM at screening.
•Additionally, because GH is currently listed as a banned substance by the World Anti-Doping Agency (WADA), National Collegiate Athletics Association (NCAA) and most professional sports agencies, we will exclude patients who are current collegiate, professional or elite athletes.