A Study of the Pharmacokinetics and Safety of Varespladib in Subjects With Normal or Impaired Renal Function

Exclusion Criteria

• •Any disease, condition and/or chronic medications which might compromise the hematologic, cardiovascular, pulmonary renal, gastrointestinal, hepatic, or central nervous system; or other conditions that might interfere with the distribution, metabolism or excretion of study drug, or would place the subject at increased risk
• •Evidence of significant respiratory, gastrointestinal or hepatic disease at screening
• •Positive screen for hepatitis B surface antigen, or HIV
• •Positive test in drugs of abuse screens or alcohol on admission to the clinic