Observing Patients With Palliative Asymptomatic Centrally Located Advanced Non-small Cell Lung Carcinoma (NSCLC)

Inclusion Criteria

• •Histologically or cytologically confirmed NSCLC
• •Central disease, as defined by tumour (either primary or nodal disease) arising or extending within a 2cm circumferential expansion from the centre of the trachea or within the zone of the proximal bronchial tree
• •Disease is visible on thoracic CT (diagnostic or simulation)
• •Asymptomatic from intra-thoracic tumour (may have background chest symptoms related to underlying COAD etc, but these symptoms must not have worsened due to tumour)
• •Patient (due to age or co-morbidities) or tumour (due to locally advanced or metastatic disease) is not suitable for radical treatment (defined as surgery or RT dose \>50Gy in 20 fractions or equivalent).
• •Previous chemotherapy, thoracic RT or surgery is allowed
• •RT to other metastases (e.g. brain, bone etc) is allowed
• ••≥ 18 years of age
• •Able to provide written informed consent