Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Alameda County Medical Center
Dexamethasone and Prednisone are both systemic corticosteroids. The study will compare a single dose of oral dexamethasone to 5 days of oral prednisone in the treatment of asthma. Oral corticosteroids are commonly prescribed following an asthma exacerbation as it has been demonstrated that these medications prevent relapse.
Oral prednisone is the most common corticosteroid prescribed for asthma relapse prevention. The half life is around 4 hours and is typically prescribed for minimally 5 days.
The study is evaluating the efficacy of a single dose of dexmethasone. The drug's efficicacy has been shown to be longer acting and up to 72 hours. A single dose would eliminate the need for a prescription for a drug like prednisone to hopefully improve compliance.
Age
18–55
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Age 18-55yo
History of asthma
Requires \> 1 albuterol nebulizer
Valid phone number
You may not be if
declines participation
Past allergic reaction to corticosteroids
Use of Oral steroids in the last 2 weeks
Pregnant
History of COPD, pulmonary fibrosis, cystic fibrosis, or other chronic lung disease
History of HIV
History of CHF
History of Diabetes mellitus
Active chickenpox (varicella) or shingles (herpes zoster)
Active TB
Requires admission to the Hospital
Requires immediate airway intervention
Clareo Health | Single Oral Dose of Dexamethasone Versus Five Days of Prednisone in Adult Asthma
