Fourteen lifetime nonsmokers with a physician diagnosis of asthma will be recruited for the study. All subjects will be allowed to use short-acting beta-adrenergic agonists as rescue medication.
Inclusion criteria:
1. Males and females, 18 to 65 years of age.
2. FEV1 60-85% of predicted on the screening day.
Exclusion criteria:
1. Women of childbearing potential who do not use accepted birth control measures; pregnant and breast feeding women.
2. Cardiovascular disease and/or use of cardiovascular medications
2\. Subjects with known beta-adrenergic agonist or glucocorticosteroid intolerance 4. Acute respiratory infection within four weeks prior to the study 5. Use, within two weeks prior to the study, of any anti-asthma medication not mentioned above
