Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University of Michigan
With
Merck Sharp & Dohme LLC
This is a cross-sectional observational study to characterize the association between obese asthmatics and the inflammatory mediators cysteinyl leukotrienes. Our hypothesis is that altered adipokine levels in obesity result in augmented cysteinyl leukotriene synthesis that play a significant role in the pathogenesis of asthma in these subjects.
Age
18–65
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
18-65 yr old adults with asthma, non-smoking for at least one year
Healthy non-smoking adults, aged 18-65 without asthma
Heavy subjects with BMI \> 30 kg/m2
Subjects with normal weight (BMI between 20-25 kg/m2)
Subject not taking anti-leukotriene therapy (Singulair, Accolate, Zyflo)
You may not be if
No chronic oral steroid use
No recent history of infection
No recent history of flare of lung disease
Clareo Health | Role of Cysteinyl Leukotrienes in the Pathogenesis of Asthma in Obesity
