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UNKNOWNNCT01141829

NADPH Oxidase Polymorphisms in Obstructive Sleep Apnea Syndrome (OSAS)

Obstructive Sleep Apnea (OSA) is associated with increased oxidative stress. The major sources of Reactive Oxygen Species (ROS) in the vasculature are the NADPH oxidases. Several polymorphisms related...

Lead sponsor: Sociedad Española de Neumología y Cirugía Torácica•1 locations•View source on ClinicalTrials.gov

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Contacts

Mónica de La Peña, MD

CONTACT

0034971175112 monica.delapena@ssib.es

Sponsors

Lead Sponsor

Sociedad Española de Neumología y Cirugía Torácica

Collaborators

Spanish Research Center for Respiratory Diseases

DESIGN: CASE-CONTROL STUDY METHODS: We are going to determine the A-930G and C242T p22phox genotypes in patients with OSA and healthy subjects recruited from sleep unit of Son Dureta University Hospital, (Palma de Mallorca, Spain). 8-Isoprostane is going to be measured as an oxidative stress marker with an 8-isoprostane EIA kit (Cayman Chemicals Company, USA) in plasma samples.

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

Yes

Exclusion Criteria

•chronic obstructive pulmonary disease, liver cirrhosis, thyroid dysfunction, rheumatoid arthritis, chronic renal failure and/or psychiatric disorders.

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: June 11, 2010Terms

Trial snapshot

StatusUNKNOWN

Phase—

Enrollment—

Start date—

Last updatedJun 11, 2010

Condition

Sleep Apnea Syndrome Oxidative Stress Single Nucleotide Polymorphism

Locations shown

Hospital Universitario Son Dureta

Palma de Mallorca, Balearic Islands

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: June 11, 2010Data synced to Clareo: May 25, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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