Nebivolol in the Supine Hypertension of Autonomic Failure

Exclusion Criteria

• •Have changed dose, frequency and or type of prescribed medication, within two weeks of study start.
• •Women of childbearing potential who are not using a medically accepted contraception.
• •Have, in the investigator's opinion, any significant cardiac, systemic, hepatic, or renal illness.
• •Diabetes mellitus or insipidus.
• •In the investigator's opinion, have clinically significant abnormalities on clinical examination or laboratory testing.
• •In the investigator's opinion, are unable to adequately co-operate because of individual or family situation.
• •In the investigator's opinion, are suffering from a mental disorder that interferes with the diagnosis and/or with the conduct of the study, e.g. schizophrenia, major depression, dementia.
• •Are not able or willing to comply with the study requirements for the duration of the study.
• •Persons on drugs with beta-blocking potential (e.g., amiodarone), persons taking scheduled or as needed nitrates and persons on drugs with alpha-blocking potential (e.g. tamsulosin).