Comparison of Depression Interventions After Acute Coronary Syndrome

Exclusion Criteria

• •Presence of non-cardiac condition likely to terminate fatally within 1 year
• •Inaccessibility for intervention or follow-up (e.g., plans to move from the area)
• •Cognitive impairment
• •Need for immediate psychiatric intervention (i.e., requiring hospitalization or psychiatric intervention within 72 hours)
• •Suicidal ideation
• •Major psychiatric co-morbidity (current or by history) including active psychosis, bipolar disorder, or overt personality disorder
• •Active substance abuse or dependency
• •Chronic renal failure (receiving chronic dialysis treatment, or estimated glomerular filtration rate"…\[eGFR\] \< 30 ml/min/1.73 m2) or moderate/severe liver disease (e.g., esophageal varices, portal hypertension, encephalopathy, GI bleeding)
• •Participation in another clinical trial for the treatment of depression.