Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Albert Einstein College of Medicine
With
Jacobi Medical Center
Age
1–3
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Children between 18 months through 3 years who had at least 2 episodes of wheezing prior to enrolment.
Positive skin tests or specific Immunoglobulin E (IgE) antibody titers to at least one of common airborne allergens: Dust Mite, cat, cockroach, mouse, dog, pollen (all allergy testing can be done at the screening visit at the study site).
The child must also fulfill the criteria for high risk of developing persistent asthma by meeting at least one of the following major conditions OR 2 of the following minor conditions:
* Major criteria: History of atopic dermatitis and/or parental history of asthma.
* Minor criteria: MD-diagnosed allergic rhinitis, wheezing unrelated to colds, blood eosinophils above 4%.
You may not be if
The child has a severe systemic condition (other than allergy or asthma) including (but not limited to) seizures, major congenital anomalies, physical and intellectual delay, cerebral palsy, chest surgery, tuberculosis, primary or secondary immunodeficiency or cardiac disorder (except a hemodynamically insignificant atrial or ventricular septum defect or heart murmur).
The child was born following 35 or less weeks of gestation.
Parental report that the child received oxygen for more than 5 days in the neonatal period, or required mechanical ventilation at any time since birth.
The child fails to thrive, defined as crossing of two major growth percentile lines during the last year.
The child has chronic lung disease of prematurity (CLDP), cystic fibrosis or any other chronic lung disease.
The child ever received immunotherapy.
The child ever received i.v. gammaglobulins or immunosuppressants (other than corticosteroids for asthma).
History of a life-threatening asthma exacerbation which required intubation and mechanical ventilation.
