A Pharmacodynamic Study to Evaluate the Effect of a Fixed Dose Combination Pill on Blood Pressure

Exclusion Criteria

• •Subjects must not have previously received any anti-hypertensive medication
• •must not have a systolic pressure \<120 mmHg or ≥160 mmHg and diastolic pressure result of \<80 mmHg or ≥100 mmHg
• •must not have had a previous coronary artery bypass graft (CABG)
• •must not have had a previous percutaneous transluminal coronary angioplasty (PTCA) with a drug-eluting stent
• •must not have severe congestive heart failure (New York Heart Classification \[NYHC\] III-IV).