The Effect of Food (High Fat and Low Fat Breakfast) on the Pharmacokinetics of Regorafenib

Exclusion Criteria

• •Regular use of medicines at the time of Screening, including prescription medications, herbal supplements and high dose vitamins
• •Sitting systolic BP \> 140 mmHg or Diastolic BP \> 90 or \< 60 mmHg
• •History of hypersensitivity or allergy
• •History of somatic or psychiatric disease/condition, which may interfere with the objectives of the study