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Over the past few years it has become clear that our understanding of bladder physiology is inadequate to explain urge incontinence. This has forced us to re-evaluate what we know and do not know about bladder function and dysfunction. This has led to the identification and study of novel systems within the bladder that may contribute to abnormal sensations. The investigators now suspect that the organic changes occurring in the bladder are not the whole story. For one group of patients with pathological urge there is growing evidence suggesting that there may be a strong psychological component. The idea now being put forward is that normal afferent peripheral information is perceived as abnormal and excessive, resulting in an increased desire to go to the bathroom: 'perceptual urge'. It is important to identify this group of patients since it will direct their treatment towards more cognitive approaches. Also, if such a psychological aetiology can be eliminated it would lead to a more focused and effective management of peripheral pathology with surgery or pharmacology.
Age
18 - No limit years
Sex
ALL
Healthy Volunteers
No
Maastricht University Medical Centre
Maastricht, Limburg, Netherlands
Start Date
June 1, 2010
Primary Completion Date
March 1, 2017
Completion Date
March 1, 2017
Last Updated
September 6, 2018
160
ACTUAL participants
Micturition diary
OTHER
Hospital Anxiety and Depression scale
OTHER
EuroQol-5D
OTHER
Self-consciousness questionnaire
OTHER
Lead Sponsor
Maastricht University Medical Center
NCT06731608
NCT07366918
Data Source & Attribution
This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.
Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.
Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.
View ClinicalTrials.gov Terms and ConditionsNCT05913219