oral corticosteroid use within 4 weeks prior to screening

current escalating immunotherapy

acute infection/antibiotic therapy within 4 weeks prior to screening, or chronic infection

pulmonary disease other than asthma

therapy with any approved monoclonal antibody or biologic agent within 12 months prior to screening

previous exposure to investigational monoclonal antibodies or biologics

A Study of RO5036505 in Patients With Moderate to Severe Asthma