Patients with mean sitSBP ≥ 200 mmHg

Patients with known hypersensitivity to Dihydropyridine or angiotensin II receptor blockers

Patients with secondary hypertension or suspected secondary hypertension

Patients with malignant hypertension

Patients who have received any medications with possible interactions with study drugs

Patients with uncontrolled diabetes

Patients with severe heart disease or severe cerebrovascular disease

Patients with clinically significant hematological test results, renal disease (serum creatinine) or liver disease (ALT or AST)

Patients with a history of malignant disease

Patients with a history of autoimmune disease

Women with a positive pregnancy test result, breast feeding or intention of pregnancy during the trial

Patients inappropriate to be included in study population due to other reasons at the discretion of the investigator

Efficacy and Safety of Amlodipine and Losartan in Patients With Essential Hypertension