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Human Papillomavirus and Oropharynx Carcinoma | Clinical Trials | Clareo Health

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UNKNOWNNCT00918710

Human Papillomavirus and Oropharynx Carcinoma

High risk papillomavirus (HR-HPV) have an oncogenic role in Oropharyngeal squamous cell carcinomas (OP-SCC) in at least 25% of the cases and the prevalence is increasing. HPV+ might be more chemo and ...

Lead sponsor: Assistance Publique - Hôpitaux de Paris•1 locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

Assistance Publique - Hôpitaux de Paris

The study has no impact on the treatment of the observed population. The clinical study include TNM status, previous story of HPV infection, smoking and alcoholic habits, treatment and outcome during 5 years. The virologic study include : HPV type, E6-E7 viral charge of HPV16, viral DNA integration in the tumoral genome, HPV16 variants, expression of HPV 16, 18, 31, 45 coding oncoproteins E6-E7 mRNA. Moreover a serologic study will be done.

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•Squamous cell carcinoma of Oropharynx proven histologically
•All stages TNM
•informed consent
•No previous or simultaneous Head Neck cancer
•Age \>18

Exclusion Criteria

•Squamous cell carcinoma other than oropharynx
•2nd synchronous SCC localization
•No consent
•age \< 18

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: April 14, 2017Terms

Trial snapshot

StatusUNKNOWN

Phase—

Enrollment362

Start dateMay 2009

Last updatedApr 14, 2017

Condition

Oropharyngeal Neoplasms

Locations shown

Tenon Hospital, APHP

Paris

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: April 14, 2017Data synced to Clareo: July 13, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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