Identifying Biomarkers for Lung Cancer Using Tissue Samples From Patients With Lung Cancer and From Healthy Participants

You may be eligible if

• DISEASE CHARACTERISTICS:
• Meets 1 of the following criteria:
• * Known or previously diagnosed lung cancer
• * Suspected lung cancer, including the following:
• * Completely resected stage I lung cancer (with no evidence of metastatic disease) for which patient is at risk for developing secondary disease
• * Suspected of having lung cancer due to clinical symptoms, such as positive sputum cytology, hemoptysis, unresolved pneumonia, persistent cough, and positive x-ray
• * Healthy volunteer
• PATIENT CHARACTERISTICS:
• WBC ≥ 2,000/mm³ but ≤ 20,000/mm³
• Platelet count ≥ 50,000/mm³
• Not pregnant
• No uncontrolled hypertension (i.e., systolic blood pressure \> 200 mm Hg, diastolic blood pressure \> 120 mm Hg)
• No unstable angina
• No known bleeding disorder
• No other contraindications for white light bronchoscopic examination
• No other contraindications for fluorescence examination
• PRIOR CONCURRENT THERAPY:
• More than 3 months since prior fluorescent photosensitizing agents (hematoporphyrin derivatives)
• More than 3 months since prior and no concurrent chemopreventative drugs (e.g., tretinoin)
• More than 6 months since prior ionizing radiation treatment to the chest
• More than 6 months since prior systemic cytotoxic chemotherapy
• No concurrent anticoagulant therapy