Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University Medical Center Groningen
Age
18–75
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Age between 18 and 65 years.
\< 10 packyears, no smoking in the last year.
The presence of allergy defined as at least one positive wheal/flare reaction (2 mm relative to control) to a skin prick test with sixteen common aero-allergens).
FEV1 \> 80% predicted.
PC20 methacholine or PC20 histamine \< 8 mg/ml.
Age between 45-75 years.
≥ 10 packyears.
FEV1 between 30% and 80% of predicted.
You may not be if
Any disease that, as judged by the Investigator, could have affected the outcome of this study.
A respiratory tract infection within 4 weeks of the start of the study.
A history of life-threatening asthma, defined as exacerbation of asthma or COPD that required intubation or was associated with hypercapnea.
History of myocardial infarction or documented myocardial ischemia.
Pregnancy, or the possibility of being pregnant (a pregnancy test will be performed in women of childbearing potential who do not use adequate anticonception as judged by the investigator).
