Gene Transfer for Cancer Pain

Inclusion Criteria

• •1. Patients with intractable pain from malignant disease with a 5 year projected survival of less than 25%.
• •2. Female patients of childbearing potential who have a negative pregnancy test and using birth control.
• •3. Patients who have not received recent treatment with a radiation, chemotherapeutic or immunotherapeutic agent and are not expected to undergo such treatment 28 days after injection of NP2.
• •4. Patients who have not had surgical stabilization/resection within 4 weeks of Screening and have no plans for additional surgical procedures.
• •5. Patients with adequate bone marrow function, IgG levels greater than 565 mg% and CD4 count greater than 500. .