Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Unity Health Toronto
With
Heart and Stroke Foundation of Canada
Age
18–70
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
Age: between 18 and 70 years of age
Healthy individuals (absence of major illnesses)
You may not be if
Primary hypertension (defined by the use of antihypertensive agents or a seated systolic blood pressure greater than or equal to 140mmHg or diastolic blood pressure greater than 90mmHg)
Secondary hypertension (defined as SBP greater than 180mmHg and DBP greater than 110mmHg)
Grade 3 hypertension (defined as SBP greater than 180mmHg and DBP greater than 110mmHg)
Diabetes
Chronic kidney disease
Liver disease
Estrogen-sensitive cancer
Heavy alcohol use
Bleeding disorders
Planned surgery
Angina
CHF
Coronary revascularization
Peripheral vascular disease
Coronary/cerebrovascular event in the last 6 months
Prescriptions of MAO inhibitors, SSRIs, diuretics, sympathomimetics, herbal therapies, medication affecting nitric oxide synthesis, and/or anticoagulent medications within the last 6 months
Sensitivity to any of the ingredients in the treatments or placebo
Chronic use of or frequent prescriptions for NSAIDs
Women of childbearing potential must not be pregnant or breast-feeding
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