History or clinical manifestations of renal impairment

Hyperglycemia \> 270 mg/dL

Receiving thiazolidenediones, Exenatide or sulfonylureas within 90 days prior to screening

Prior use of Acipimox which is known under the name Olbetam within 90 days prior to screening.

Diagnosed major depression within the last 2 years requiring hospitalization

History of chronic insulin therapy for glycemic control

Evaluate the Safety and Tolerability of INCB019602 When Administered With Metformin in Patients With Type 2 Diabetes