Dopamine Agonist for Hemispatial Neglect and Motor Deficit Post Stroke

Inclusion Criteria

• •Confirmed clinical diagnosis of right-hemisphere stroke.
• •Able to give informed consent.
• •Presence of left hemispatial neglect defined by a deficit in finding leftward targets on standard cancellation or visual search tests68-70. (A deficit on the line bisection test alone will not be sufficient for inclusion, as a previous study shows that there is no significant relationship between performance on this test and spatial working memory capacity37).
• •Presence of motor deficits: all patients will have suffered from first-ever clinically defined stroke resulting in weakness of at least wrist and finger extensors, and hand interossei (to \</= 4+ on the Medical Research Council scale), at the time of recruitment.
• •Age over 18 years.
• •More than 9 days since stroke-onset (Note that on our protocol patches do not commence until a minimum of 6 days after the study begins. Thus patients will not receive drug / placebo until a minimum of 15 days post-stroke).
• •Able and willing to use patches of drug/placebo and assessments at regular intervals as defined by the protocol.
• •Able to comply with study requirements.
• •If female and of child-bearing potential, subject has a negative serum pregnancy test within two days of enrollment.