Lead Sponsor

University of California, Irvine

Age

0 - 0 years

Sex

ALL

Healthy Volunteers

No

•Preterm infants born at post menstrual ages of 23-33 weeks gestation Enrollment occurs at post menstrual age of 30 to 35 weeks.if their projected stay based on standard clinical criteria is four weeks after enrollment
•Enrollment occurs at post menstrual age of 30 up to 35 weeks, if their projected stay based on standard clinical criteria is 4 weeks after enrollment.
•Birth weight appropriate for gestational age (AGA) using current CDC growth charts. AGA is defined as plus or minus 2 standard deviations above the mean or above the third percentile.
•Tolerating full enteral feeds at greater than or equal to 100kcal/kg/day

•Evidence of chromosomal or other major genetic abnormalities
•Existence of current diseases or syndromes including:
•central nervous system or other neurological abnormalities chronic lung disease of prematurity requiring chronic use of corticosteroids, musculoskeletal diseases
•positive infant toxicology screen(urine) for drugs or alcohol
•Both parents are under the age of 18 years
•Babies with tracheostomy
•Babies receiving ventilator assistance with breathing
•Babies receiving IV fluids