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COMPLETEDPhase 3NCT00527995

Acute Effects of Sildenafil on Endothelial Function in People With Diabetes

This is a double-blind, placebo-controlled, cross-over trial using a single dose of 100 mg sildenafil or placebo in 40 subjects with T2DM without known cardiovascular disease. Effects on haemodynamic ...

Lead sponsor: Ruhr University of Bochum•1 locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

Ruhr University of Bochum

Age

35 - 70 years

Sex

MALE

Healthy Volunteers

No

Inclusion Criteria

•age 35-70
•type 2 diabetes mellitus
•impotence
•with and without hypertension, hypercholesteremia

Exclusion Criteria

•patients with history of cardiovascular and malignant disease,
•advanced nephropathy (creatinine≥2.2mg/dl)
•hepatopathy (liver enzymes higher than the double of normal values)
•patients taking nitrates
•CHF: NYHA \> II
•Stable angina: CCS \> II

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: September 11, 2007Terms

Trial snapshot

StatusCOMPLETED

PhasePHASE3

Enrollment40

Start dateAug 2001

Last updatedSep 11, 2007

Condition

Type 2 Diabetes Mellitus Endothelial Dysfunction

Locations shown

German Diabetes Center

Düsseldorf, North Rhine-Westphalia

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: September 11, 2007Data synced to Clareo: July 13, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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