A Study To Investigate The Effect Of Inhaled Fluticasone Propionate On The Bronchial Responsiveness To Leukotriene D4 In Asthmatics Patients

You may be eligible if

• Inclusion:
• Diagnosed history of asthma
• Non smoker last two years
• \< 5 pack years
• FEV1 \>70% of predicted
• Mild and stable asthma
• Only using short acting b2-agonist as rescue for the last 4 weeks
• Have a history of atopy.
• Exclusion:
• Any significant respiratory disease, other than asthma
• Subjects with seasonal asthma may not be included if they are in their season
• Use of oral or inhaled glucocorticosteroid for the last 3 months and long-acting or oral b2-agonists, anticholinergic bronchodilators, cromones, antihistamines, theophyllines and antileukotrienes within two weeks
• Upper or lower RTI within 6 weeks
• Evidence of any disease that in the investigators mind would affect the results of the study
• Participating in another study within 4 weeks
• Females who are pregnant, intend to be or who are lactating
• Methacholine PD20 \> 454mcg
• Negative scin prick test