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COMPLETEDPhase 4NCT00442845

Establish The Benefits Of Using Various Starting Doses Of Atorvastatin On Achievement Of Cholesterol Targets (ACTFAST)

Physicians tend to always use the lowest dose of statins to initiate therapy even in subjects who require large reductions in cholesterol. The study evaluates if selecting the starting dose based on b...

Lead sponsor: Pfizer's Upjohn has merged with Mylan to form Viatris Inc.•121 locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

Pfizer's Upjohn has merged with Mylan to form Viatris Inc.

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•High cholesterol blood levels (LDL-cholesterol above 100 mg/dL up to 220 mg/dL.
•Triglycerides up to 600 mg/dL.
•History of coronary artery disease (ex.: heart attack, angina), stroke, diabetes or at high risk of such events

Exclusion Criteria

•Pregnancy or lactation, use of high statin doses (\>40mg) at baseline, liver or renal problems, use of other drugs that would interfere with evaluation of efficacy or cause safety problems, uncontrolled hypertension, diabetes or hypothyroidism, recent cardiac event of procedure, high baseline CPK levels

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: February 18, 2021Terms

Trial snapshot

StatusCOMPLETED

PhasePHASE4

Enrollment2,080

Start dateJan 2003

Last updatedFeb 18, 2021

Condition

Coronary Arteriosclerosis Diabetes Mellitus, Type 2 Cerebrovascular Accident Dyslipidemia Peripheral Vascular Disease

Locations shown

Pfizer Investigational Site

Mississauga, Ontario

Pfizer Investigational Site

Calgary, Alberta

Pfizer Investigational Site

Edmonton, Alberta

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: February 18, 2021Data synced to Clareo: May 10, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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