Daptomycin as an Adjuvant Agent in the Treatment of Enterococcal Native Valve Endocarditis.

Exclusion Criteria

• •Pregnancy or breast feeding
• •Creatine phosphokinase levels over two times the upper limit of normal
• •Renal insufficiency or dialysis requirement.
• •Presence of chronic indwelling bloodstream catheters or foreign body devices suspected as primary or secondary sites of enterococcal infection unamenable to removal or replacement
• •Inability to discontinue or abstain from use of a HMG CoA reductase inhibitor during the study period.
• •Hypersensitivity to any of the study medications.
• •Any condition that, in the investigator's opinion, may interfere with protocol compliance including, but not limited to, active substance abuse and/or dementia.
• •Prosthetic valve endocarditis