Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
GlaxoSmithKline
Age
0–65
Sex
FEMALE
Healthy volunteers
Accepted
You may be eligible if
Healthy ambulatory postmenopausal woman defined as being amenorrheic for at least 2 years
Non-smoker
Weight \>110 lbs (\>50 kg)
Body mass index within the range 19 - 29.9 kg/m2
are capable of giving written informed consent
You may not be if
Have any clinically relevant abnormality identified on the screening history and physical or laboratory examination, 12-lead surface electrocardiogram (ECG) and/or 24 hour Holter, including QTc \> 450 msec
Test positive urine drug screen or alcohol
Test positive for HIV, hepatitis B virus or hepatitis C virus
Smoker or have a history of smoking or use of nicotine containing products within one year of the study or \>10 pack-year history of smoking overall
have a history of regular alcohol consumption exceeding 7 units/week (1 unit = 5 ounces of wine or 12 ounces of beer or 1.5 ounces of hard liquor) within 6 months of screening
have a history of drug abuse within 6 months of the study
have participated in a trial with an investigational drug within 30 days or 5 half-lives (whichever is longer) preceding the first dose of study medication
use of prescription or non-prescription drugs (including calcium tablets, calcium containing antacids, aspirin or nonsteroidal anti-inflammatory drugs), vitamins, herbal and dietary supplements, within 14 days prior to the first dose of study medication.
have consumed of grapefruit containing products within 14 days prior to the first dose of study medication
have donated of blood in excess of 500 mL within 56 days prior to dosing
have evidence of kidney or liver disease
have a history of significant gastrointestinal disease or a gastrointestinal surgical procedures
are sensitive to any of the study medications or components thereof
have a history of cardiovascular disease
have medical conditions which might alter bone metabolism
have a serum parathyroid hormone (iPTH) test, or vitamin D levels outside the normal range
Clareo Health | A Study Of SB-751689, Atorvastatin, Ketoconazole, And Rosuvastatin In Health Postmenopausal Women.
