Gastric Motor Function Measurement in Dyspepsia and Normal Subjects

Exclusion Criteria

• •No structural or metabolic diseases/conditions that affect the gastrointestinal system.
• •Unable to stop medications 48 hours prior to the study that:
• •* Alter GI transit including laxatives, magnesium or aluminum-containing antacids, prokinetics, erythromycin, narcotics, anticholinergics, tricyclic antidepressants, SSRI and newer antidepressants.
• •* Analgesic drugs including opiates, NSAID, COX 2 inhibitors
• •* Systemic antifungal drugs
• •* Carbamazepine, glucocorticoids, phenobarbital, phenytoin, rifampin, but also grapefruit juice.
• •* Benzodiazepines NOTE: Low stable doses of thyroid replacement, estrogen replacement, low dose aspirin for cardioprotection and birth control pills or depot injections are permissible.
• •Female subjects who are pregnant or breast feeding.
• •Significant cardiovascular, respiratory, renal, hepatic, gastrointestinal, hematological, neurological, psychiatric, or other disease that interfere with the objectives of the study.
• •Subjects who have participated in another clinical study within the past 30 days.
• •Previous gastric or intestinal surgery (except appendectomy , cholecystectomy or hysterectomy).