Pelvic Exenteration in Treating Patients With Recurrent Cervical Cancer

Inclusion Criteria

• •Diagnosis of cervical cancer
• •* Any histology
• •* Documented or suspected central pelvic disease with or without pelvic sidewall fixation from tumor and/or radiation fibrosis
• •Meets 1 of the following stage criteria:
• •* Recurrent disease, defined as reappearance of disease after a complete clinical response lasting ≥ 1 month
• •* Persistent disease, defined as presence of disease by biopsy ≥ 3 months after completion of primary therapy
• •Must have received prior primary treatment, including any of the following:
• •* Surgery with or without post operative radiotherapy with or without chemotherapy
• •* Primary radiotherapy with or without chemotherapy
• •* Neoadjuvant chemotherapy followed by surgery
• •* Neoadjuvant chemotherapy followed by surgery with or without radiotherapy or chemotherapy
• •Plans to undergo pelvic exenteration to remove the pelvic disease within 14 days after study entry
• •* Deemed to be a good surgical candidate
• •* No evidence of distant disease or disease that is felt to be unresectable by physical examination
• •* Patients with suspicious pelvic or para-aortic nodal disease as the only site(s) of extrapelvic disease are eligible at the discretion of the surgeon