Pentasa Once Daily in Ulcerative Colitis for Maintenance of Remission

Exclusion Criteria

• •1. Patients with evidence of other forms of inflammatory bowel disease, idiopathic proctitis or infectious disease
• •2. Patients allergic to acetylsalicylic acid and other salicylate derivates aspirin or salicylates derivatives
• •3. Patients who used mesalazine \> 2.5 grams orally in the previous month,
• •4. Patients who used rectal mesalazine \> 3 grams per week in the previous month
• •5. Use of corticosteroids (oral and/or rectal routes) within the last month
• •6. Intake of immunosuppressants within the last 3 months
• •7. Patients with (known) significant hepatic (up to 2 x upper limit of normal) or (known) renal function abnormalities, to 1.5 x upper limit of normal values
• •8. Patients with history or physical examination findings indicative of active alcohol or drug abuse
• •9. Patients with a history of disease, including mental/emotional disorders, that would interfere with their participation in the study
• •10. Women who are pregnant or nursing (non-menopausal women who are sexually active and do not use effective contraceptives, as judged by the investigator, must have a negative pregnancy test)
• •11. Patients who participated in another clinical study in the last 3 months
• •12. Patients who were previously participating in this study
• •13. Patients with any other disease that may influence the study assessment, such as malignant disease, etc.
• •14. Patients who are unable to comply with any requirements of the protocol
• •15. Patients who are unable to write or read local language.