Safety and Efficacy Study of Vitrase for Clearance of Severe Vitreous Hemorrhage

Exclusion Criteria

• •Corneal or lenticular abnormalities that preclude fundus observation
• •Ongoing ocular infection, inflammation or history of herpetic corneal lesion
• •Current or prior retinal detachment or retinal tears or breaks or intraocular tumor
• •More than 1 severe vitreous hemorrhage within 6 months
• •Previous vitrectomy for any reason
• •Hemorrhage is exclusively pre-retinal, or old \& organized
• •Prior Vitrase for intravitreal injection in either eye
• •No light perception in either eye at any time
• •Known contraindications to study medication
• •Sickle cell disease