Immediate need for renal replacement therapy.

Treatment resistant oedema or nephrotic syndrome.

Need for treatment with corticosteroids, non-steroidal antiinflammatory drugs, or immunosuppressive drugs.

Albuminuria greater than 1000mg /24h and or less than 20mg/24h.

Total cholesterol \< 135mg/dl or not need for statins treatment.

Renovascular hypertension

Malignant hypertension

MI, cerebrovascular accident within last year, severe peripheral vascular disease, CHF, chronic hepatic disease.

Angiotensin converting enzyme inhibitors and angiotensin II receptors blockers within one month prior to randomization.

A serum creatinine concentration \>265 umol/L

Antialbuminuric Effects of Valsartan and Lisinopril