Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Novartis
Age
18–any
Sex
FEMALE
Healthy volunteers
Not accepted
You may be eligible if
Body mass index (BMI) must be ≥ 27 and \< 35
Symptoms of impaired exercise capacity (e.g. who report shortness of breath on exertion when questioned) reported at Visit 1 or patients who have a history of shortness of breath which improved under diuretic therapy
LV ejection fraction must be \> 45% measured by echocardiography at Visit 2.
Impaired exercise capacity measured by VO2max at Visit 4:
VO2max \>14 and \< 22 ml ⋅kg-1 ⋅min-1
You may not be if
Mean sitting diastolic blood pressure (MSDBP) ≥ 110 mmHg and/or Mean sitting systolic blood pressure (MSSBP) ≥ 180 mmHg
LVEF ≤ 45 %
Inability to completely discontinue all previous antihypertensive medications safely for the duration of the study
Heavy smokers (\>20 cigarettes/day)
Clareo Health | VALENCE: Valsartan Versus Atenolol on Exercise Capacity in Hypertensive Overweight Postmenopausal Women
