Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Bristol-Myers Squibb
With
Sanofi
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Willing to provide written informed consent
Subjects must have uncontrolled hypertension defined as:
* average systolic blood pressure between 160 mmHg and 180 mmHg (while diastolic blood pressure is less than 110 mmHg) or
* average diastolic blood pressure between 100 mmHg and 110 mmHg (while systolic blood pressure is between 130 mmHg and 180 mmHg)
Subjects must be willing to discontinue their antihypertensive medication, if applicable.
Men and women, ages 18 and older will be included.
Women of childbearing potential (WOCBP) must be using an adequate method of contraception to avoid pregnancy throughout the study and for up to one week after the study in such a manner that the risk of pregnancy is minimized. WOCBP must have a negative serum or urine pregnancy test within 72 hours prior to the start of study medication.
You may not be if
Women who are pregnant or breastfeeding
Known or suspected secondary hypertension
Hypertension emergencies or stroke within the past 12 months.
Heart attack, angina or bypass surgery within the past six months.
Significant kidney disease
Significant liver disease
Systemic lupus erythematosus
Gastrointestinal disease or surgery that interfere with drug absorption
Cancer during the past five years excluding localized squamous cell or basal cell carcinoma of the skin
Currently pregnant or lactating
Mental condition (psychiatric or organic cerebral disease) rendering the subject unable to understand the nature, scope, and possible consequences of the study
