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1–20 of 1,327
Completed
Vitamin D Therapy in Patients With Systemic Lupus Erythematosus (SLE)
The purpose of this study is to test the safety and effectiveness of different doses of vitamin D in patients with Systemic Lupus Erythematosus (SLE).
NCT00418587
·
Charleston, South Carolina
Completed
Efficacy and Safety of Low-dose IL-2 in Patients With SLE: a Multicenter, Randomised, Placebo-controlled Trial
The management of active systemic lupus erythematosus (SLE) is challenging due to the heterogeneous nature of the disease and lack of specific treatment.
NCT04077684
·
Beijing
Not yet recruiting
The Safety, Tolerability, Pharmacokinetics, Immunogenicity and Preliminary Efficacy of HC022 Injection in Subjects With SLE/CLE
The primary objective of this phase Ib study is to evaluate the safety and tolerability of multiple-ascending, subcutaneous (SC) doses of HC022 in SLE/CLE subjects.
NCT07306585
·
Beijing, Beijing Municipality
Completed
Lymphocyte Depletion and Stem Cell Transplantation to Treat Severe Systemic Lupus Erythematosus
This study will examine a new approach to treating patients with severe systemic lupus erythematosus (SLE) that involves collecting stem cells (cells produced by the bone marrow…
NCT00076752
·
Bethesda, Maryland
Withdrawn
An Exploratory Clinical Study of Anti-CD19/BCMA Chimeric Antigen Receptor NK Cell Injection in the Treatment of IgA Nephropathy
A single arm, open-label pilot study is designed to evaluate the safety and effectiveness of anti-CD19/BCMA CAR NK cells (KN5601) in patients with IgA nephropathy
NCT06926985
·
Jieyang, Guangdong
Completed
Searching for Diagnostic/Prognostic Biomarkers in SLE With Renal Involvement by Proteomic Techniques
Objective: To search for potential biomarkers obtained by non-invasive methods (24-hour urine collection) that distinguish between patients diagnosed with systemic lupus…
NCT03687138
·
Bilbao, Bizkaia
Completed
Dexamethasone Treatment for Congenital Heart Block (CHB) in Newborns With Lupus
Some newborns are born with congenital heart block (CHB), a condition occurring in babies with neonatal lupus.
NCT00007358
·
New Haven, Connecticut and 3 others
Completed
COVID-19 Vaccine in Immunosuppressed Adults With Autoimmune Diseases
This study will evaluate the Moderna RNA-based COVID-19 vaccine currently approved by Health Canada in people with rheumatic diseases.
NCT04806113
·
Montreal, Quebec
Completed
A Study of the Safety and Pharmacokinetics of CNTO 136 in Patients With Cutaneous Lupus Erythematosus and Systemic Lupus Erythematosus
The main purpose of this study was to evaluate the safety and pharmacokinetics (PK, the action of a drug in the body over a period of time) of multiple intravenous (IV)…
NCT01702740
Active not recruiting
Intergenerational Study of War-Affected Youth
War-related violence is a leading driver of mental disorders and illness affecting children in low- and middle-income countries (LMICs).
NCT06440460
·
Freetown
Withdrawn
Tissue Sodium in Autoimmune Disease
This pilot study will test the hypothesis that a low sodium diet will decrease sodium (23Na) magnetic resonance imaging-determined skin sodium concentrations in patients with…
NCT02525835
·
Nashville, Tennessee
Recruiting
A Clinical Study of MK-1045 in People With Lupus or Rheumatoid Arthritis (MK-1045-004)
This study looks at a study medicine called MK-1045 in people with lupus and rheumatoid arthritis (RA).
NCT07363590
·
Southport, Queensland and 20 others
Completed
BG9588 (Anti-CD40L Antibody) to Treat Lupus Nephritis
The purpose of this study is to investigate whether the experimental drug BG9588 can be used to treat lupus nephritis more effectively and with less toxicity than standard…
NCT00001789
·
Bethesda, Maryland
Completed
A Crossover Study to Compare RAYOS to IR Prednisone to Improve Fatigue and Morning Symptoms for SLE
To compare the effect of RAYOS® versus immediate-release (IR) prednisone on fatigue as measured by Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-F).
NCT03098823
·
Los Angeles, California and 20 others
Terminated
Mediterranean vs. High-Fermented-Food Diet Adherence on Inflammation in Lupus
This is a 4-month randomized controlled trial to evaluate the feasibility of 'good and very good' adherence to the Mediterranean dietary pattern and to a high-fermented-food diet…
NCT05379725
·
Gainesville, Florida
Unknown
Creatine Supplementation in Pediatric Rheumatology
Creatine supplementation may improve strength, muscle mass, bone mass and muscle function in healthy and elderly people.
NCT01217320
·
São Paulo, São Paulo
Completed
Efficacy and Safety of Anifrolumab Compared to Placebo in Adult Subjects With Active Systemic Lupus Erythematosus
The purpose of this study is to evaluate the efficacy and safety of an intravenous treatment regimen of anifrolumab versus placebo in adult participants with moderately to…
NCT02446899
·
Covina, California and 112 others
Unknown
Contemplation-Based Intervention and Health Outcomes RCT in Lupus Patients
The objective of this study is to test the efficacy of an innovative contemplative-based and caregiver-inclusive intervention can modify pathogenic processes in systemic lupus…
NCT04032496
Recruiting
A Study of CLN-978, a Subcutaneously Administered CD19-directed T Cell Engager, in Subjects With Systemic Lupus Erythematosus
Phase 1b, open-label study of CLN-978 administered subcutaneously in patients with Moderate to Severe Systemic Lupus Erythematosus (SLE).
NCT06613360
·
Avondale, Arizona and 19 others
Not yet recruiting
Uromodulin as a Biomarker in Lupus Nephritis
Evaluation of Uromodulin as a biomarker of renal histological activity/ Chronicity indices in lupus nephritis
NCT07763834
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