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1–20 of 1,466
Completed
A Study of Perampanel as Add-on Therapy in Adult and Adolescent Participants With Focal Seizures
The primary objective of the present study will be to assess the effectiveness of add-on perampanel in participants with focal seizures in a real-life clinical setting.
NCT04257604
Completed
Propofol-remifentanyl Versus Dexmedetomidine in Awake Craniotomy: Impact on Electroclinical Seizure Activity
Awake craniotomy require a cooperative patient during resection neurosurgery phase.
NCT05103735
·
Udine
Completed
Study Evaluating LAMICTAL Extended-Release Therapy Added To Current Seizure Treatments In Patients With Primary Generalized Tonic-Clonic Seizures (PGTC) Seizures
This study is being conducted to compare the efficacy and safety of LAMICTAL (lamotrigine) extended-release with placebo in the treatment of Primary Generalized Tonic-Clonic…
NCT00104416
·
Anniston, Alabama and 145 others
Unknown
Diagnostic Value of Smartphone Video in Epileptic Seizures
1. Accuracy of seizure diagnosis based on smartphone seizure semiology anaysis 2.
NCT05574725
Completed
A Study to Investigate the Efficacy and Safety of ZX008 (Fenfluramine Hydrochloride) as an Adjunctive Therapy in Children and Adults With Lennox-Gastaut Syndrome
This is a two-part, multicenter, double-blind, parallel-group, placebo controlled study to evaluate the effect of ZX008 when used as adjunctive therapy for the treatment of…
NCT03355209
·
Tucson, Arizona and 71 others
Completed
Drug Utilization and Safety Events Among Children Using Esomeprazole, Other Proton Pump Inhibitors or H2-receptor Antagonists
The purpose of this study is 1.
NCT01338363
·
Utrecht
Completed
Epileptic Psychoses and Their Link With Ictal Emotions and Consciousness
Background : Psychiatric comorbidities are common in epilepsy, affecting 50 to 70% of patients, especially when the epilepsy is focal and drug-resistant.
NCT06960811
·
Nancy, Lorraine
Recruiting
Evaluation of the Epilepsy-related Quality of Life, Seizure-related Accidents and Validation of the Mjn-SERAS Solution in the Normalised Patient Environment with Real-World Data
The study will be prospective, multicentre, postmarketing clinical study, with a controlled and randomized design, to perform the analysis of 130 subjects with a clinical…
NCT05845255
·
Kork and 5 others
Recruiting
Sustained Effort Network for Treatment of Status Epilepticus/European Academy of Neurology Registry on Refractory Status Epilepticus (SENSE-II/AROUSE)
SENSE-II/AROUSE is a prospective, multicenter registry for patients treated for SE.
NCT05839418
·
Linz and 10 others
Recruiting
Infrared Photobiomodulation in Humans With Epilepsy
Drug-resistant epilepsy represents roughly 40% of people with epilepsy. It is very challenging to stop seizures in this condition, and the treatment options are limited.
NCT07145489
·
Boston, Massachusetts
Active not recruiting
A Phase 3 Study to Examine the Efficacy and Safety of ZX008 in Subjects With CDKL5 Deficiency Disorder.
This is a Phase 3 Study to examine the efficacy and safety of ZX008 in children and adults with cyclin-dependent kinase like-5 (CDKL5) deficiency disorder (CDD).
NCT05064878
·
Birmingham, Alabama and 45 others
Terminated
Sabril for Complex Partial Seizures in Adult Tolerability Study (TS) Patients
This is an open-label, phase 4 study to examine the safety and efficacy of vigabatrin (Sabril) in Tuberous Sclerosis patients, a subset of the larger refractory complex partial…
NCT01266291
·
Philadelphia, Pennsylvania
Recruiting
Safety and Tolerability Study of SPN-817 in Adult Patients With Treatment Resistant Epilepsy
This study will evaluate the safety and tolerability of SPN-817 in adults with treatment resistant seizures
NCT05518578
·
Jacksonville, Florida and 9 others
Unknown
Value of Von Willebrand Factor and Copeptin Assay in Children With Febrile Seizures at Sohag University Hospital
Febrile seizures are one of the most common clinical diseases in pediatric neurology. It occurs between 6 months and 6 years of age and occurs in \~2-5% of children.
NCT05008458
·
Sohag
Unknown
Diagnostic and Prognostic Criteria of EEG in Neonatal Convulsions at Assiut University Children Hospital
Diagnostic and prognostic criteria of EEG in neonatal convulsions at Assiut University Children Hospital
NCT06106425
Not yet recruiting
A Study to Assess utiLity of BIoEP as an Early Prognostic Indicator for Predicting Anti-Seizure Medication (ASM) Efficacy
This multisite prospective clinical study is to investigate the relationship between seizure type and frequency with the BioEP result during ASM titration in newly diagnosed…
NCT06354868
Completed
A Pilot Study of Efficacy and Tolerability of Levetiracetam Monotherapy in Subjects With Childhood Absence Epilepsy
Childhood absence epilepsy (CAE) is a form of generalized epilepsy syndrome.
NCT00361010
·
Cleveland, Ohio and 1 other
Completed
Replacing Protein Via Enteral Nutrition in a Stepwise Approach in Critically Ill Patients
In this study, we will explore the feasibility of a randomized controlled trial that will compare high protein dose from ICU day 6 to 14 with moderate protein intake.
NCT03480555
·
Jeddah and 1 other
Completed
E2007 Given as Adjunctive Therapy in Patients With Refractory Partial Seizures
The primary objective of this study is to determine the maximal tolerated dose (MTD) of E2007 given twice daily (bid) or once a day (qd) in patients with refractory partial-onset…
NCT00144690
·
Little Rock, Arkansas and 4 others
Completed
Efficacy and Safety of RAD001 in Patients Aged 18 and Over With Angiomyolipoma Associated With Either Tuberous Sclerosis Complex (TSC) or Sporadic Lymphangioleiomyomatosis (LAM)
This study will evaluate the safety and efficacy of RAD001 in treating patients with Angiomyolipoma associated with Tuberous Sclerosis Complex or Sporadic Lymphangioleiomyomatosis.
NCT00790400
·
Birmingham, Alabama and 24 others
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