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1–20 of 8,559
Completed
First Line Treatment by FOLFIRINOX for Patients With a Rectum Cancer With Synchronous Non Resectable Metastasis
The FOLFIRINOX protocol seems a promising protocol as attack treatment of a rectum cancer, with an objective response rate of about 70 %.
NCT01674309
·
Amiens and 36 others
Completed
M7824 in Patients With Metastatic Colorectal Cancer or With Advanced Solid Tumors With Microsatellite Instability
This phase Ib/II trial studies how well anti-PD-L1/TGFbetaRII fusion protein M7824 (M7824) works in treating patients with colorectal cancer (or with other solid tumors with…
NCT03436563
·
Houston, Texas
Completed
Study of Erbitux (Cetuximab) in Patients With Metastatic Colorectal Carcinoma
This is a phase II, multicenter, target enrollment of 250 evaluable patients, open-label study of cetuximab in patients with refractory, metastatic colorectal carcinoma.
NCT00044863
·
Saint Charles, Missouri
Completed
Intensity-Modulated Radiation Therapy, Fluorouracil, and Mitomycin C in Treating Patients With Invasive Anal Cancer
RATIONALE: Specialized radiation therapy that delivers a high dose of radiation directly to the tumor may kill more tumor cells and cause less damage to normal tissue.
NCT00423293
·
Tucson, Arizona and 171 others
Completed
Arginase Inhibitor INCB001158 as a Single Agent and in Combination With Immune Checkpoint Therapy in Patients With Advanced/Metastatic Solid Tumors
This study is an open-label Phase 1/Phase 2 evaluation of INCB001158 as a single agent and in combination with immune checkpoint therapy in patients with advanced/metastatic solid…
NCT02903914
·
Mobile, Alabama and 19 others
Completed
A Phase II, Double Blind Study of 2 Doses of ZACTIMA™(ZD6474) in Combination With FOLFIRI vs FOLFIRI Alone for the Treatment of Colorectal Cancer in Patients
The purpose of this study is to assess the efficacy and safety of 2 doses of ZACTIMA™ (ZD6474) in combination with FOLFIRI vs FOLFIRI alone for the treatment of colorectal cancer…
NCT00454116
·
Ann Arbor, Michigan and 20 others
Recruiting
Short-Course RT Plus CAPOX and Tislelizumab vs Long-Course CRT Plus Tislelizumab for Locally Advanced Rectal Cancer
To explore the complete response (CR) rate of modified short-course radiotherapy plus CAPOX and Tislelizumab versus Long-course Chemoradiotherapy plus Tislelizumab for locally…
NCT07469306
·
Fuzhou, Fujian and 2 others
Unknown
PTC Drug Sensitivity Detection to Guide Postoperative Adjuvant of Colorectal Cancer
The research objectives is to compare vitro 3D drug sensitivity test results of micro tumor (PTC) with the clinical outcomes of patients, evaluate the consistency between the test…
NCT05978349
·
Beijing, China/Beijing
Completed
PRESEPT Study: Evaluation of SEPT9 Biomarker Performance for Colorectal Cancer Screening
The purpose of this study is to collect blood specimens and clinical data from screening guideline eligible individuals designated by their physician to receive a screening…
NCT00855348
·
Boca Raton, Florida and 22 others
Unknown
Enhanced Recovery After Surgery Program for Colorectal Cancer: a Multi-center Study (ERASC1)
This study is aimed to evaluate the safety of applying enhanced recovery after surgery for colorectal cancer.
NCT03126058
·
Changzhou, Jiangsu and 22 others
No longer available
Expanded Access of Onvansertib With FOLFIRI and Bevacizumab for the Second-Line Treatment of Participants With KRAS-Mutated Metastatic Colorectal Cancer
This is an expanded access program for eligible participants designed to provide access to onvansertib in combination with FOLFIRI and bevacizumab.
NCT04446793
Completed
The Value of Narrow Band Imaging in Stratifying Patients for Endoscopic Resection or Surgery
Magnification narrow band imaging (NBI) can make accurate evaluation in in predicting of invasive depth of colorectal neoplasia.
NCT01521104
Unknown
S-1/Leucovorin (SL) Versus sLV5FU2 as the First-line Treatment for Elderly Patients With Colorectal Cancer
This phase II trial on the assumption that S-1 combined with Leucovorin may have better efficacy and safety than simplified 5-FU/LV infusion therapy in elderly patients with…
NCT01193452
·
Shanghai, Shanghai Municipality
Enrolling by invitation
A Prospective Single-center Randomized Controlled Trial of Robotic Surgery With Transrectal Resection Specimens (NOSES-IV) and Traditional Assisted Robotic Surgery for the Treatment of High Rectal and Sigmoid Colon Cancer
This study aimed to compare the short-term efficacy of robotic radical resection of high rectal cancer and sigmoid colon cancer (NOSES-IV) with transrectal resection specimens and…
NCT06906952
·
Nanchang
Unknown
The Auxiliary Effects of Fucoidan for Locally Advanced Rectal Cancer Patients
This is a double-blind, randomized, placebo-controlled, parallel study.
NCT04342949
·
Kaohsiung City
Unknown
Pembrolizumab and Disitamab Vedotin in HER2-expressing Metastatic Colorectal Cancer
This is an open-label, multi-center, phase Ⅱ study.
NCT05333809
Not yet recruiting
Pattern of Treatment and Outcomes of Locally Advanced Rectal Carcinoma
the study will discuss different pattern of treatment and the outcomes of locally advanced rectal carcinoma as a retrospective study.
NCT07363863
Not yet recruiting
A Prospective, Single-Arm, Multicenter, Phase II Clinical Study of Iparomlimab and Tuvonralimab (QL1706) Combined With Cetuximab and mFOLFIRI Regimen as First-Line Treatment for Recurrent or Metastatic Colorectal Cancer
This is a prospective, single-arm, multicenter, phase II clinical study designed to evaluate the efficacy and safety of iparomlimab and tuvonralimab (QL1706) combined with…
NCT07874438
·
Nanjing, Jiangsu
Recruiting
Real-world Efficacy and Safety of Neoadjuvant Dostarlimab in Patients With dMMR/MSI-H Locally Advanced Rectal Cancer
This is an observational, retrospective-prospective, multicentre trial enrolling all patients included in the AIFA monitoring registry of Dostarlimab for the indication in rectal…
NCT07269249
·
Naples and 1 other
Not yet recruiting
Artificial Intelligence-based Dietary Care System
Patients with rectal cancer complicated by low anterior resection syndrome who undergo anal-preserving surgery may experience severe distress in daily life due to changes in bowel…
NCT07637565
·
Taipei
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