Clinical Trials Search | Clareo Health

Showing 1-2 of 2 trials

Artesunate Ointment for the Treatment of High Grade Vulvar Intraepithelial Neoplasia (HSIL VIN2/3)

NCT03792516

This is a Phase I, proof-of-concept treatment study to evaluate the safety, tolerability and feasibility of topical artesunate ointment to treat high grade vulvar intraepithelial neoplasia (HSIL VIN2/3).

Vulvar DysplasiaHPV-Related Vulvar Intraepithelial NeoplasiaPreinvasive Vulvar Disease+2 more

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins15 participantsStarted Apr 2019

Baltimore, Maryland, United States • Cleveland, Ohio, United States • Cleveland, Ohio, United States +1 more locations

COMPLETEDPhase 3

A Randomized Trial of Surgical Treatments for Vulvar and Vaginal Dysplasia

NCT00394758

1. To compare the recurrence rate between the use of laser vaporization and ultrasonic surgical aspiration in the treatment of vulvar and vaginal dysplasias 2. To compare healing related complications, post-operative pain, and scarring between the two procedures.

Vulvar DysplasiaVaginal Dysplasia

University Hospitals Cleveland Medical Center150 participantsStarted Jan 2000

Cleveland, Ohio, United States

Data from ClinicalTrials.govTerms

Showing 1-2 of 2 trials

COMPLETEDPhase 1

Artesunate Ointment for the Treatment of High Grade Vulvar Intraepithelial Neoplasia (HSIL VIN2/3)

NCT03792516

This is a Phase I, proof-of-concept treatment study to evaluate the safety, tolerability and feasibility of topical artesunate ointment to treat high grade vulvar intraepithelial neoplasia (HSIL VIN2/3).

Vulvar DysplasiaHPV-Related Vulvar Intraepithelial NeoplasiaPreinvasive Vulvar Disease+2 more

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins15 participantsStarted Apr 2019

Baltimore, Maryland, United States • Cleveland, Ohio, United States • Cleveland, Ohio, United States +1 more locations

COMPLETEDPhase 3

A Randomized Trial of Surgical Treatments for Vulvar and Vaginal Dysplasia

NCT00394758

1. To compare the recurrence rate between the use of laser vaporization and ultrasonic surgical aspiration in the treatment of vulvar and vaginal dysplasias 2. To compare healing related complications, post-operative pain, and scarring between the two procedures.

Vulvar DysplasiaVaginal Dysplasia

University Hospitals Cleveland Medical Center150 participantsStarted Jan 2000

Cleveland, Ohio, United States

Data from ClinicalTrials.govTerms

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Artesunate Ointment for the Treatment of High Grade Vulvar Intraepithelial Neoplasia (HSIL VIN2/3)

A Randomized Trial of Surgical Treatments for Vulvar and Vaginal Dysplasia

Artesunate Ointment for the Treatment of High Grade Vulvar Intraepithelial Neoplasia (HSIL VIN2/3)

A Randomized Trial of Surgical Treatments for Vulvar and Vaginal Dysplasia