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Preoperative Radiotherapy and Immunotherapy for Sinonasal and Anorectal Mucosal Melanoma

NCT05546827

The goal of this clinical research study is to learn if pre-operative radiation therapy after starting immune checkpoint inhibition can help patients with sinonasal or anorectal melanoma have better outcomes

Sinonasal MelanomaAnorectal Melanoma

M.D. Anderson Cancer Center40 participantsStarted Sep 2022

Houston, Texas, United States

RECRUITINGPHASE2

Toripalimab Combined With Radiotherapy and Chemotherapy in the Treatment of SNMM After Endoscopic Surgery

NCT04879654

Phase II, single-arm, prospective clinical study of Toripalimab(a PD-1 antibody) combined with radiotherapy and chemotherapy in the treatment of sinonasal malignant mucosal melanoma after endoscopic surgery.

Malignant MelanomaSinonasal Melanoma

Eye & ENT Hospital of Fudan University45 participantsStarted May 2021

Shanghai, Shanghai Municipality, China

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Preoperative Radiotherapy and Immunotherapy for Sinonasal and Anorectal Mucosal Melanoma

Toripalimab Combined With Radiotherapy and Chemotherapy in the Treatment of SNMM After Endoscopic Surgery

Preoperative Radiotherapy and Immunotherapy for Sinonasal and Anorectal Mucosal Melanoma

Toripalimab Combined With Radiotherapy and Chemotherapy in the Treatment of SNMM After Endoscopic Surgery