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Study of Epcoritamab in R/R Primary Diffuse Large B-cell Lymphoma of the CNS Treated With Lenalidomide and Rituximab

NCT06931652

The purpose of this phase 2 study is to evaluate the efficacy and safety of epcoritamab in subjects with relapsed or refractory primary diffuse large B-cell lymphoma of the Central Nervous System treated with rituximab and lenalidomide.

Primary CNS Lymphoma (PCNSL)

The Lymphoma Academic Research Organisation60 participantsStarted Sep 2025

Bordeaux, France • Caen, France • Clermont-Ferrand, France +10 more locations

COMPLETEDPhase 2

Treatment of Primary CNS Lymphoma ( FTD )

NCT05274139

The purpose of this study is to evaluate the efficacy and safety of FTD regiment (fotemustine, temozolomide and dexamethasone ) for patients with primary CNS lymphoma.

Primary CNS Lymphoma (PCNSL)

Mingzhi Zhang20 participantsStarted Mar 2017

Zhengzhou, Henan, China

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Study of Epcoritamab in R/R Primary Diffuse Large B-cell Lymphoma of the CNS Treated With Lenalidomide and Rituximab

Treatment of Primary CNS Lymphoma ( FTD )

Study of Epcoritamab in R/R Primary Diffuse Large B-cell Lymphoma of the CNS Treated With Lenalidomide and Rituximab

Treatment of Primary CNS Lymphoma ( FTD )