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RECRUITINGPhase 2

Pfs230D1 + R21 in Matrix-M1 in African School Children and Adults

NCT07147400

This is a Phase 2, randomized, double-blind, controlled study designed to evaluate the safety, tolerability, immunogenicity, vaccine efficacy, and functional activity of Pfs230D1-CRM197 conjugate vaccine with R21 nanoparticle vaccine formulated on Matrix-M1. Participants (9-50 years of age) will be drawn from Bancoumana, Mali and the surrounding areas.

Prevention of Malaria Transmission and Clinical Malaria

Serum Institute of India Pvt. Ltd.1,200 participantsStarted Aug 2025

Bamako, Mali

Data from ClinicalTrials.govTerms